India’s HPV vaccine rollout: from a welcome launch to an elimination strategy
DOI:
https://doi.org/10.56450/JEFI.2026.v4i01.001Keywords:
HPV vaccine, cancerAbstract
India’s recent nationwide rollout of human papillomavirus (HPV) vaccination marks an important moment in cancer prevention. The national campaign, launched in February 2026, offers a single dose of quadrivalent HPV vaccine to eligible 14-year-old girls free of cost through government health facilities, with plans to continue vaccine availability through routine immunisation sessions after the initial campaign phase (1,2).
Prophylactic HPV vaccines are most effective when administered before exposure to infection, making early adolescent vaccination central to prevention. In its 2022 position paper, the World Health Organization (WHO) recommended a one- or two-dose schedule for girls aged 9–14 years, with HPV vaccination positioned as a foundational pillar of the global strategy to eliminate cervical cancer as a public health problem (3). Importantly, India has contributed directly to the evidence supporting a single-dose approach. A multicentre prospective cohort study from India reported that a single dose of quadrivalent HPV vaccine provided high protection against persistent HPV 16/18 infection at 10 years, with efficacy comparable to two- and three-dose schedules (4).
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1. Press Information Bureau, Government of India. Update on National HPV Vaccination Programme (Internet). New Delhi: Ministry of Health and Family Welfare; 2026 Mar 17 (cited 2026 Mar 25). Available from: https://www.pib.gov.in/PressReleasePage.aspx?PRID=2241079
2. Press Information Bureau, Government of India. Prime Minister Shri Narendra Modi launches nationwide HPV vaccination campaign (Internet). New Delhi: Government of India; 2026 Feb 28 (cited 2026 Mar 25). Available from: https://www.pib.gov.in/PressReleasePage.aspx?PRID=2233906
3. World Health Organization. Human papillomavirus vaccines: WHO position paper, December 2022. Wkly Epidemiol Rec. 2022;97(50):645-72.
4. Basu P, Malvi SG, Joshi S, Bhatla N, Muwonge R, Lucas E, et al. Vaccine efficacy against persistent human papillomavirus HPV 16/18 infection at 10 years after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre, prospective, cohort study. Lancet Oncol. 2021;22(11):1518-29.
5. Times of India. HPV vaccination coverage doubles to 12% in 10 days in Haryana, Gurgaon at 10% (Internet). 2026 May 7 (cited 2026 Mar 25). Available from: https://timesofindia.indiatimes.com/city/gurgaon/hpv-vaccination-coverage-doubles-to-12-in-10-days-in-haryana-gurgaon-at-10/articleshow/130868997.cms
6. World Health Organization. Global strategy to accelerate the elimination of cervical cancer as a public health problem. Geneva: World Health Organization; 2020.
7. Rosser EN, Wysong MD, Rosen JG, Limaye RJ, Park S. HPV vaccine delivery strategies to reach out-of-school girls in low- and middle-income countries: a narrative review. Vaccines (Basel). 2025;13(5):433.
8. Josten K, Rose Dhar R, Reshmi B, Natti Krishna V, Vennila J. Barriers to HPV vaccination among adolescent girls in India: A scoping review. Indian J Med Res. 2025;162(6):743-753.
9. Xu MA, Pant S, DiClemente RJ. Factors affecting human papillomavirus vaccination: A review of individual, interpersonal, and structural factors affecting vaccine uptake among adolescents. Vaccine. 2026 May 10;81:128563.
10. Brisson M, Kim JJ, Canfell K, Drolet M, Gingras G, Burger EA, et al. Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries. Lancet. 2020;395(10224):575-90.
11. Canfell K, Kim JJ, Brisson M, Keane A, Simms KT, Caruana M, et al. Mortality impact of achieving WHO cervical cancer elimination targets: a comparative modelling analysis in 78 low-income and lower-middle-income countries. Lancet. 2020;395(10224):591-603.
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Copyright (c) 2026 Manya Prasad, Umesh Kapil, Pradeep Aggarwal (Author)
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