Demographic Pattern of Pancreatitis Patients in India – A Hospital-based Study
DOI:
https://doi.org/10.56450/JEFI.2025.v3i01.010Keywords:
Pancreatitis, Tropical Pancreatitis, Epidemiology, Demographic Trends, Pancreatic DisordersAbstract
Background: Pancreatitis, an inflammatory disease of the pancreas, is emerging as a significant health concern globally, with an increasing incidence in India. Historically, the disease was first identified in India in 1937, and since then, research efforts have expanded, focusing on regional patterns and causative factors. Methodology: This hospital-based study analyzes the demographic and clinical characteristics of 2,050 patients diagnosed with pancreatitis between January 1997 and November 2024, treated at leading hospitals across India. Key parameters, including age, gender, region, dietary habits, and lifestyle patterns, were evaluated to identify demographic trends and risk factors associated with the disease. Result: The study revealed a predominantly male population (83%) with an average age of 24 years and a significant proportion (75%) of adult patients aged 19–45 years. Similarly, only 33.6% of patients reported alcohol consumption, and tobacco use was documented in 18.4% of cases. Furthermore, genetic predisposition was observed in 8.8% of patients, while gallstone-related pancreatitis accounted for 5% of cases. Conclusion: The findings indicate the need for broader epidemiological studies to understand the regional and lifestyle factors contributing to the rising incidences of pancreatitis in India.
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References
1. Navarro S. Historical review of our knowledge of acute pancreatitis. Revisión histórica de algunos conocimientos sobre pancreatitis aguda. Gastroenterol Hepatol. 2018;41(2):143.e1-143.e10.
2. Kini MG. Multiple pancreatic calculi with chronic pancreatitis. Br J Surg. 2005;25(99):705–6.
3. Moyer MS. Pediatric Clinical Advisor. Elsevier; 2007.
4. Desai N, Kaura T, Singh M, Willingham FF, Rana S, Chawla S. Epidemiology and characteristics of chronic pancreatitis-do the east and west meet? Gastro Hep Adv [Internet]. 2022;1(6):942–9.
5. Garg PK, Tandon RK. Survey on chronic pancreatitis in the Asia-Pacific region. J Gastroenterol Hepatol [Internet]. 2004;19(9):998–1004.
6. Whitcomb DC, North American Pancreatitis Study Group. Pancreatitis: TIGAR-O version 2 risk/Etiology Checklist with topic reviews, updates, and use primers: TIGAR-O version 2 risk/etiology checklist with topic reviews, updates, and use primers. Clin Transl Gastroenterol [Internet]. 2019;10(6):e00027.
7. Nature.com. Accessed Mar 25, 2025. Available from: https://www.nature.com/subjects/pancreatitis.
8. Sawant P, Mishra P. Chronic pancreatitis - Indian scenario. Medicine Update API. 2005;418–24.
9. Prakash VB, Prakash M, Prakash VS, Tiwari S, Sharma S, Jaryal VP, Tewari J. Changing Demography of Pancreatitis Patients in India - A Hospital Based Study”. Acta Scientific GastrointestinalDisorders. 2019;2(7):8–11.
10. Prakash B, Prakash S, Sati ST. Ayurvedic treatment protocol in the management of pancreatitis: A nonrandomized observational study. Int J Ayurveda Res [Internet]. 2024;5(3):205–9.
11. Prakash VB, Prakash S, Negi N, Sati ST. Observational research on the effect of an Ayurvedic treatment protocol in patients of hereditary pancreatitis. J Ayurveda Integr Med [Internet]. 2024;15(3):100913.
12. Weiss FU, Laemmerhirt F, Lerch MM. Acute pancreatitis: Genetic risk and clinical implications. J Clin Med [Internet]. 2021;10(2):190.
13. Chen Q, Li J, Ma J, Yang X, Ni M, Zhang Y, et al. Fibroblast growth factor 21 alleviates acute pancreatitis via activation of the Sirt1-autophagy signalling pathway. J Cell Mol Med [Internet]. 2020;24(9):5341–51.
14. Yu X. Effects of biological clock on acute pancreatitis: Roles and mechanisms. Med Hypotheses [Internet]. 2023;179(111152):111152.
15. Hernández Santiago K, López-López AL, Sánchez-Muñoz F, Cortés Altamirano JL, Alfaro-Rodríguez A, Bonilla-Jaime H. Sleep deprivation induces oxidative stress in the liver and pancreas in young and aging rats. Heliyon. 2021;7(3):e06466
16. Jaworek J, Szklarczyk J, Jaworek AK, Nawrot-Porąbka K, Leja-Szpak A, Bonior J, et al. Protective effect of melatonin on acute pancreatitis. Int J Inflam [Internet]. 2012;2012:173675.
